flow cytometry – Communicable Diseases Research

Jinhua Qinggan granules attenuates acute lung injury by promotion of neutrophil apoptosis and inhibition of TLR4/MyD88/NF-κB pathway

Article

Published on 2023-01-302022-11-16
Journal: Journal of ethnopharmacology
[Category] 신종인플루엔자, 치료기술,

Ultrasensitive monitoring of SARS-CoV-2-specific antibody responses based on a digital approach reveals one week of IgG seroconversion

Article

Published on 2022-12-012022-11-15
Journal: Biosensors & bioelectronics
[Category] COVID19(2023년), SARS, 진단, 치료기술,

The long term vaccine-induced anti-SARS-CoV-2 immune response is impaired in quantity and quality under TNFα blockade

Article

Published on 2022-12-012022-11-15
Journal: Journal of medical virology
[Category] COVID19(2023년), SARS, 변종, 진단,

[키워드] Activation acute respiratory syndrome alteration analysed anti-SARS-CoV-2 anti-SARS-CoV-2 IgG anti-TNF-α appear Autoimmune Autoimmune diseases blockade bystander Cell changes in chronic inflammatory disease Cohort comparable Control coronavirus COVID-19 Decline drugs Effect Efficacy ELISA flow cytometry groups healthy humoral immune response IgG immune cell populations immune response immunoblot investigated less Live virus Necrosis Neutralization assay neutralize neutralizing antibody neutralizing capacity Older omicron Patient patients plasma Plasma cell recipient reduced response SARS-CoV-2 second vaccination significantly T cell subset titre TNF-α TNFα tumor necrosis factor inhibitors tumor necrosis factor-α vaccination vaccination. Vaccine variants of concern virus VoC was increased while
[DOI] 10.1002/jmv.28063 PMC 바로가기

Combined assessment of S- and N-specific IL-2 and IL-13 secretion and CD69 neo-expression for discrimination of post-infection and post-vaccination cellular SARS-CoV-2-specific immune response

Article

Published on 2022-11-012023-07-09
Journal: Allergy
[Category] COVID19(2023년),

[키워드] COVID flow cytometry lymphocytes. SARS-CoV-2 T cells
[DOI] 10.1111/all.15406 PMC 바로가기

Deep immunophenotyping reveals biomarkers of multisystemic inflammatory syndrome in children in a Latin American cohort

Article

Published on 2022-11-012022-11-15
Journal: The Journal of Allergy and Clinical Immunology
[Category] SARS, 바이오마커, 진단,

[키워드] acute respiratory syndrome Biomarker Biomarkers CCL5 Cell cellular response characterized chemokine children Chilean clinical clinical feature Cohort Complication convalescent coronavirus COVID-19 CXCL10 CXCL8 Cytokine storm deep degranulation disease dysregulation elevated enzyme-linked immunosorbent enzyme-linked immunospot flow cytometry gastrointestinal involvement humoral identify IL-10 IL-18 IL-6 immune dysregulation immune response Immunity Inflammation Inflammatory intestinal inflammation laboratory biomarker Latin life-threatening Ligand MIS-C mononuclear cell MOST motif multisystemic multisystemic inflammatory syndrome in children. natural killer neutralizing antibody neutralizing antibody assays NK cell NK cell deficiency occur organ Patient patients predict representing reveal robust severe multisystemic severity Shock significantly stools susceptibility sustained syndrome T-cell activation underlie was increased was performed
[DOI] 10.1016/j.jaci.2022.09.006 PMC 바로가기

Ganoderma microsporum immunomodulatory protein acts as a multifunctional broad-spectrum antiviral against SARS-CoV-2 by interfering virus binding to the host cells and spike-mediated cell fusion

Article

Published on 2022-11-012022-11-15
Journal: Biomedicine & pharmacotherapy = Biomédecine & phar
[Category] SARS, 변종, 치료제,

[키워드] ACE2 ACE2-expressing cells acute respiratory syndrome alleviate Antiviral binding blocked Broad-spectrum antiviral against SARS-CoV-2 caused Cell Cell fusion cell lines cell-free virus cells characteristic coronavirus Delta determine Diseases downregulation Effect evaluated examined flow cytometry fluorescence microscopy fluorescent Fungal immunomodulatory proteins fusion GMI HEK293T cell host cell immunomodulatory immunoprecipitation in vitro Infection Infectivity ingredient inhibit inhibited inhibitor Interaction investigated less mechanism multifunctional omicron Protein pseudotyped virus reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pseudovirus SARS-CoV-2 pseudovirus SARS-CoV-2 pseudovirus infection SARS-CoV-2 spike protein SARS-CoV-2 variant spike mutation spike variant spike variants Strains Viral binding. virus were used
[DOI] 10.1016/j.biopha.2022.113766 PMC 바로가기

Impact of the New Coronavirus Infection on the Immune System of Children and Adolescents in the Region of the Russian Federation

Article

Published on 2022-10-212022-11-15
Journal: International Journal of Environmental Research an
[Category] COVID19(2023년), SARS, 진단,

[키워드] absence Active disease Adolescent age analysed analyses Analysis biochemical carried categories caused CD3+CD4+ cellular immunity changes in children Clinical features consequence COVID-19 deviation Diagnosis disease disease stage Epidemiology Federation FIVE flow cytometry group growth Human immune system IgA IgG IgG and IgM IgM Immune status immune system Immunity Immunoglobulin immunograms immunological immunology immunology. immunoregulation Impact Infection interval introduced laboratory diagnosis lack leukocytes Lymphocytes methodology Mutation New New coronavirus NK cell pandemic pathogen Patient patients Perm Krai phagocytic phagocytosis professional public health QR code Quantitative analysis Racial Region Research Russian population SARS-CoV-2 SARS-CoV-2 vaccination selected serological severity System T helper the disease Treatment was performed
[DOI] 10.3390/ijerph192013669 PMC 바로가기

Differences in the immune response elicited by two immunization schedules with an inactivated SARS-CoV-2 vaccine in a randomized phase 3 clinical trial

Article

Published on 2022-10-132022-11-15
Journal: eLife
[Category] COVID19(2023년), SARS, 변종, 진단,

[키워드] Activation acute respiratory syndrome antibody approved blood sample Brazil CD4 cellular Chilean China circulating antibodies clinical clinical trial Concentration CoronaVac coronavirus coronavirus disease correlation COVID-19 difference dose Efficacy elicited Emergency use enrolled evaluate evaluated exhibited expression flow cytometry healthy Human humoral immune response humoral immune responses IFN-γ immune response immunization immunogenicity data immunology inactivated Indonesia Inflammation interferon marker Medicine Ministry of Health mononuclear cell multicenter neutralizing antibody neutralizing capacity pandemic PBMCs performed Peripheral blood Phase 3 phase 3 clinical trial phase 3 trial Production progression promote Randomized reported robust Sample SARS-CoV-2 SARS-CoV-2 vaccine secretion separated single center Stimulation T cell Trial Turkey Vaccine Vaccines Vaccines. variants of concern virus VOCs Volunteer were assessed
[DOI] 10.7554/eLife.81477 PMC 바로가기

Central and effector memory T cells in peripheral blood of patients with interstitial pneumonia: preliminary clues from a COVID-19 study

Article

Published on 2022-10-102022-11-15
Journal: Respiratory Research
[Category] COVID19(2023년), SARS, 바이오마커,

[키워드] acute phase addition affected Analysis biological marker CD3+ cells CD4 CD8 Cell cell population central memory Central memory T cells control group control patient controls COVID-19 COVID-19 diagnosis cross-sectional decrease described differential expression disease early phase effector effector memory Effector memory T cells flow cytometry group homeostasis hospital Hospital admission immune increase interstitial interstitial lung involvement interstitial pneumonia lymphocyte subpopulation Lymphocyte subpopulations memory memory T memory T cells Patient patients with pneumonia performed Peripheral blood peripheral lymphocyte Pneumonia positive pre-existing T-cell protocol reactivity recruited Research Respiratory disease SARS-CoV-2 SARS-CoV-2 PCR SARS-CoV-2. severe COVID-19 patients significant decrease significant increase study participant study period subpopulations subset T cell T-cell therapeutic viral respiratory infections were assessed
[DOI] 10.1186/s12931-022-02190-8 PMC 바로가기

Dynamic Evaluation of Natural Killer Cells Subpopulations in COVID-19 Patients

Article

Published on 2022-10-062022-11-15
Journal: International Journal of Molecular Sciences
[Category] COVID19(2023년), SARS, 바이오마커,